Vitadone Background Information
Nutritional status and immune function in cocaine users and heroin abusers and in methadone treated subjects
Absract
The plasma levels of some essential nutrients and the lymphocyte CD4 to CD8 ratio were measured in four groups of individuals that included: (a) cocain and (b) heroin abusers, (c) methadone treated and (d) healthy subjects. Folate and B-carotene levels were lower in the three drug groups while vitamin C was lower in the methadone and heroin subjects. Vitamin E levels were borderline low in the methadone and cocaine groups. The methadone group also showed a significantly higher level of lipid peroxidation which correlated well with the low values observed for the antioxidant nutrients. Interestingly, the methadone group was the only one with a significantly reduced lymphocyte CD4 /CD8 ratio.
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